• Comet Corner: Using Clinical Observation to Study the Effects of Stress on the Human Brain

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    Comet Corner Mug

    Corticosteroids are commonly prescribed medications that decrease inflammation and suppress the immune system. This presentation will discuss how the side effects of these medications can help us understand the effects of stress and the stress hormone cortisol on the human brain. The presenter will also discuss the impact of recently obtaining an MBA at UT Dallas on his research.

    FEATURED GUEST SPEAKER: E. Sherwood Brown, M.D., Ph.D., M.B.A. ’20, is Professor with Tenure, Vice Chair for Clinical Research, the Aradine S. Ard Chair in Brain Science, Chief of the Division of Clinical Neuroscience and Director of the Psychoneuroendocrine Research Program in the Department of Psychiatry at The University of Texas Southwestern Medical Center, Dallas, Texas.

    He received B.A. and Ph.D. degrees in chemistry from Texas Christian University, an M.D. degree from The University of Texas Medical School at Houston, and completed psychiatry residency, on the research track, followed by a research fellowship, at The University of Texas Southwestern Medical Center. In 2020, he obtained an M.B.A. with a healthcare organization leadership concentration, from the University of Texas at Dallas.

    He is board-certified in both psychiatry and the subspecialty of consultation-liaison psychiatry. For many years he has conducted research on co-occurring conditions in people with mood disorders.

    He has over 200 publications and has been principal investigator on 18 grants from the National Institutes of Health and 20 from private foundations and the State of Texas, in this and related areas. He on the board of directors of the Academy of Consultation-Liaison Psychiatry and chairs their research committee. He serves on several journal editorial boards including the Journal of Affective Disorders and is Editor-in-Chief of the Journal of Dual Diagnosis.

    In 2002 he was co-recipient of the Gerald L. Klerman Award for clinical research from the National Alliance for Research in Schizophrenia and Depression for a research project on the effects of long-term corticosteroid therapy on memory and the hippocampus.

    MODERATOR: Tyler Miller, M.D., is chief of medicine at the Dallas VA hospital, professor of medicine at UT Southwestern Medical School, vice-chair of medicine at UT Southwestern, and a member of the advisory board of the Ackerman Center for Holocaust Studies at UT Dallas.

    As chief of medicine at the VA, Dr. Miller has worked to expand high-quality specialty medical services to veterans in North Texas and recently manage to COVID-19 pandemic in this group of patients. The Dallas VA is a major teaching hospital for UT Southwestern medical students, residents, and fellows. He also has a basic research laboratory on the UT Southwestern main campus where he studies basic aspects of kidney disease.


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