Dr. Adrianna Shembel has received $2,910,950 from National Institutes of Health (NIH) to further her research on Central Modulation-Paired Motor Rehabilitation for Recurrent Laryngeal Nerve Injury. This award supports Dr. Shembel’s innovative approach to improving laryngeal motor function following recurrent laryngeal nerve (RLN) injury, which often results in vocal fold paralysis, impacting critical functions such as swallowing and verbal communication.

The objective of this project is to explore the use of neuromodulation paired with motor-specific behaviors like swallowing to promote central neuroplasticity and restore vocal fold movement. By utilizing a rat model of RLN injury, Dr. Shembel aims to better understand the neural mechanisms involved in motor recovery and investigate the functional effects of neuromodulation on vocalization, vocal fold movement, and airway defense. This research will employ advanced techniques, including laryngoscopy, ultrasonic vocalization analysis, and corticobulbar mapping, to quantify and track progress across acute and chronic stages of injury.

The results of this research have the potential to significantly improve treatment outcomes for patients suffering from RLN injury-induced impairments, offering a novel therapeutic approach that could enhance both the functional and psychosocial well-being of affected individuals. This work exemplifies the scholarly value and impact that aligns with the mission of National Institutes of Health and promises to contribute meaningfully to the field of biomedical research.