The National Institutes of Health (NIH) awarded Dr. Noa Ofen $1,741,495 for her research on the Development of Memory Networks in Children. This research project will address the challenge of understanding the neurophysiological mechanisms behind memory retrieval. This cognitive ability significantly progresses throughout childhood but is often injured in various psychiatric and neurological disorders. The research will also assess how dynamic interactions between critical brain regions, such as the prefrontal cortex (PFC), medial temporal lobe (MTL), and visual cortices, contribute to memory retrieval.

With a focus on three main objectives of classifying strategic control mechanisms intervened by the PFC, examining the role of mnemonic content in the MTL and visual cortices, and linking memory retrieval data to consistent memory scores, this project will apply advanced methods like intracranial EEG (iEEG) and fMRI. This research will enhance the perception of how memory systems develop and provide valuable understanding for the plan of involvement to help alleviate the loss of memory in children, especially those affected by epilepsy.

By fostering a deeper understanding of the developing brain, this work will contribute to the field of cognitive neuroscience and have extensive translational significance for treating memory disorders in both pediatric and adult populations. This research aligns with the NIH’s commitment to advancing the scientific understanding of brain function and improving therapeutic approaches for neurological conditions.