Dr. Ted Price was awarded nearly $800 thousand from the National Institute of Health (NIH) in conjunction with Thomas Jefferson University to study extracellular mechanisms regulating synaptic functions and pain plasticity. His research aims to determine the mechanism mediating the EphB-NDMAR interaction, characterize molecules and other tools to disrupt this interaction, and determine whether preventing the EphB-NMDAR interaction will alleviate chronic pain. The project will develop new knowledge defining a novel mechanism for synaptic plasticity, and enable progress toward development of completely new therapeutic interventions for neurological disorders and understanding of neuronal development.