A Certificate of Confidentiality (CoC) is an additional resource Investigators can use to protect data collected from a research participant against disclosure during any civil, criminal, administrative, legislative, or other proceeding – at any level. Issued by a number of federal agencies (NIH, NIJ, FDA), this tool is not limited to studies funded by the federal government. During this session, Amanda Boone answers many common questions about a CoC to help Investigators – who are working on sensitive research topics and collecting identifying characteristics or subject names – understand how to protect participant privacy through the use of a CoC.